Obesity: One diet may not be enough to lose weight

Jean-Benoit Legault, The Canadian Press

MONTREAL — Some adults who suffer from obesity and cannot lose weight by following a low-calorie diet can improve their condition by also adopting a physical activity program. activity, Ontario researchers found.

This may make it possible to better personalize the strategies offered to obese adults who want to lose weight.

“It is very important to understand that not everyone will respond in the same way to an intervention,” said researcher Denis Blondin, of the Faculty of Medicine at the University of Ottawa. There are people who are very sensitive to exercise, there are others who are very sensitive to diet, then you have to find the best strategy for that person.

The exercise program, he said, gives women who “resist” a profile more similar to people who lose weight by changing their diet.

Patients with “diet resistant” obesity are in the lower 20% of the rate of weight loss on a low calorie diet.

The researchers collected clinical data from more than 5,000 patient records. Finally, the records of 228 were analyzed and it was recommended that a subgroup of 20 obese women undergo a strictly controlled exercise program, which is an exercise (treadmill, strength training) that consists of of 18 progressive sessions offered three times per week for six weeks.

The use of bioinformatics and machine learning methods in the analysis of skeletal muscles shows that exercise can improve the metabolism of these muscles and the capacity to lose weight in obese people who know- food resistance.

The patients in question are those whose obesity is difficult to treat and are often criticized for not respecting the dietary restrictions imposed when they do not lose weight.

“We found that these women, even if they were dedicated to eating like the rest of the group, had more difficulty losing weight through dieting, while with exercise, they lost weight than women who are very sensitive to. the (restricted calorie diet)”, explained Mr. Blondin.

It should not be concluded, he added, that patients who resist weight loss with dietary changes will also not respond to an exercise program. On the contrary, they may respond as well, or better, than those who were able to lose weight on a diet.

Two out of three Canadian adults are overweight or obese, according to Statistics Canada.

The findings of this study were published in the medical journal eBioMedicine.

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